49ers' Kittle out, Bosa & Ward in vs. Rams

UPDATE: 49ers tight end George Kittle missed Friday's practice and has been ruled out of Sunday's game against the Los Angeles Rams.

Cornerback Charvarius Ward and defensive end Nick Bosa, who popped up on the injury report with a rib injury mid-week, are active.

The original story follows:

The San Francisco 49ers just can't seem to catch a break right now.

According to multiple reports, tight end George Kittle and cornerback Charvarius Ward missed Thursday's practice. According to ESPN's Adam Schefter, Kittle is experiencing tightness in his hamstring, and his status for Sunday's game against the Los Angeles Rams "is in question."

Meanwhile, Ward is nursing injuries to his knee and hamstring.

The 49ers are already without star running back Christian McCaffrey for at least the next three weeks after he was placed on injured reserve due to calf tightness and Achilles tendinitis, and Deebo Samuel, who will miss "a couple weeks" due to a calf strain.

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