Trey Lance out, Trent Williams doubtful for 49ers-Colts

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49ers rookie quarterback Trey Lance will sit out Sunday night’s contest against the Indianapolis Colts as he continues to recover from a left knee sprain he suffered in Week 5.

The team issued a rough injury report Friday afternoon, as defensive tackles Javon Kinlaw and Maurice Hurst are also out and star left tackle Trent Williams is listed as doubtful.

This is a concerning development for the 49ers, especially for the No. 3 overall pick, Lance, who is losing valuable practice and potential game reps in his rookie season.

While other top first-year quarterbacks like Trevor Lawrence, Zach Wilson, Justin Fields and Mac Jones have combined to make 21 starts so far this season, Lance only has six meaningful quarters of play under his belt. Remember, the 49ers used this year's firs