The Lions haven't played a game and their injury report is already 10 players long.
The biggest name on there: Kenny Golladay. And Golladay's chances of playing Sunday against the Bears don't look good.
Golladay tweaked his hamstring in practice Wednesday, which forced him to the sidelines both Thursday and Friday. He's officially listed as doubtful for the season-opener.
Detroit's offense will be without another key piece in right tackle Halapoulivaati Vaitai. He's officially out for Sunday after missing practice for the second straight day due to a foot injury.
Tyrell Crosby will likely step in for Vaitai, who signed a five-year, $45 million contract with the Lions in the offseason. He hadn't missed a game the past three seasons.
Detroit's revamped offensive line will have its hands full with Chicago's deep defensive front. If there's any good news for the Lions, it's that Bears DE Robert Quinn will likely miss Sunday's game as well. He's listed as doubtful with an ankle injury.
The Lions also got good news on D'Andre Swift, who was a full participant at Friday's practice and is good to go for Sunday. The rookie running back had been nursing a hip injury.
On the flip side, there's a chance Jeff Okudah will have to wait at least a week to make his NFL debut. He was limited at practice the past two days with a hamstring issue and is listed as questionable for Sunday.
As for the rest of the injury report, WR Danny Amendola (hamstring), DL Da'Shawn Hand (groin), DE Julian Okwara (knee) is and CB Darryl Roberts (groin) are all questionable, while S C.J. More (hamstring) and TE Hunter Bryant (hamstring) are both out.