Wide receiver Will Fuller V and cornerback Bradley Roby are out with hamstring injuries. Safety Tashaun Gipson Sr. is out with back and wrist injuries. Cornerback Lonnie Johnson Jr. and offensive lineman Greg Mancz are out in the concussion protocol.
Mancz has been in the concussion protocol since the week of Sept. 29, when the Texans lost to the Carolina Panthers.
Fuller injured his hamstring in the Texans' Oct. 20 road loss to the Indianapolis Colts. Roby was injured in the Texans' 31-24 victory against the Chiefs.
Gipson has been dealing with lingering injuries for several weeks and was sidelined against the Raiders. He played only nine defensive snaps against the Colts in the previous week.
Johnson suffered a concussion in the most recent game against the Raiders.