Sunday's game between the Steelers and Titans in Tennessee is being postponed.
In an official statement, the NFL said the game could be played either Monday or Tuesday. The postponement is to allow additional time for further daily COVID-19 testing, the league's statement said.
ESPN's Dianna Russini first reported the news.
Four Tennessee Titans players tested positive for coronavirus along with five personnel, leading them to suspend in-person club activities Tuesday.
The Minnesota Vikings, who played the Titans this past Sunday and visit NRG Stadium this Sunday, also shut down their facilities temporarily.