Top fantasy football waiver wire pickups for Week 4
In the large majority of 2021 fantasy football drafts, with the exception of a small handful, the first two picks off the board were Christian McCaffrey and Dalvin Cook. In Week 3, McCaffrey exited the game with a hamstring injury that will ultimately cost him multiple weeks. Cook didn't suit up due to a lingering ankle injury that kept him sidelined from practice all week and gave way to a strong performance from Alexander Mattison.
That wasn't the ideal scenario for those teams who drafted at No. 1 and No. 2 overall, but such is life in the cruel — yet so, so alluring — world of fantasy football.

The waiver wire is one of your only friends in this unpredictable landscape, and using it to your advantage is one of the keys to success in outwitting your league mates and building a strong enough team to compete despite the injuries, underperforming players and other obstacles in the way of glory. Let's see what Week 4 has in store.
Only players owned in fewer than 50 percent of leagues will be considered. All statistics courtesy of Fantasy Pros.