Texans running backs Joe Mixon and Dameon Pierce did not practice Wednesday due to injuries.
Mixon is dealing with an ankle injury and Pierce is still recovering from a hamstring injury. If the Texans have to play without them, it puts the spotlight on Cam Akers.
In addition, the Texans are also without centers Juice Scruggs (groin) and Jarrett Patterson (calf), who worked out to the side at Wednesday's practice. Backup tight end Brevin Jordan was also placed on the injured reserve list, meaning he'll miss a minimum of four games.
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