Did Trent Brown have a setback?

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FOXBOROUGH -- The Patriots were once again down a bunch of offensive linemen at practice on Thursday.

Isaiah Wynn (COVID-19 list), Michael Onwenu (COVID-19 list), Trent Brown (calf) and Shaq Mason (ab) all missed their second consecutive practice. In addition, cornerback Shaun Wade and practice squad offensive lineman Drake Jackson were not present, either.

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Specific to Brown, it appears he had setback with his calf injury. The offensive tackle suffered in the injury in Week 1 and hasn't played in a game since, but returned to practice the Friday of Week 2 in a limited capacity. He then was limited all of Week 3 and 4, but has missed the first two days of practice in Week 5.

Brown aside, the Patriots will have to do some shuffling up front this week. It's unclear whether Wynn and/or Onwenu can play and then Mason missing two straight practices is not a good sign. Ted Karras, Justin Herron, Yasir Durant and even practice squad player James Ferentz could be in line for extended snaps Sunday in Houston.

At 1-3, the Patriots are desperate for a win.

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