Chicago outrighted left-hander Manny Bañuelos, outfielder Ryan Cordell, infielder Ryan Goins and infielder Matt Skole to Triple-A Charlotte. All will become minor-league free agents after the conclusion of the World Series.
The White Sox's 40-man roster now sits at 35 players.
Bañuelos, 28, had a 6.93 ERA and 1.84 WHIP in 16 games, including eight starts, this past season.
Cordell, 27, hit .221 with seven homers, 24 RBIs and a .645 OPS in 97 games.
Goins, 31, hit .250 with two homers, 10 RBIs and a .681 OPS in 52 games.
Skole, 30, hit .208 with no homers, six RBIs and a .511 OPS in 27 games.