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Police officers said they received information that 26-year-old Victor Yan was hiding in a home on Woodland Avenue near South 67th Street.
When marshals from the Fugitive Task Force and police went into the home around 6:15 a.m., Yan ran upstairs and climbed onto the roof.
After a brief standoff, he eventually gave up and was taken away to face homicide and related charges.
Police say Yan stabbed 28-year-old Brett Berdini at 10th and Race streets on Oct. 16, 2018 after he and his girlfriend left a nearby bar.