Mayim Bialik reveals incident that tested her friendship with Neil Patrick Harris: ‘I felt terrible’

College photo of Mayim Bialik and Neil Patrick Harris
Photo credit Photo by Imeh Akpanudosen/Getty Images / Dia Dipasupil/Getty Images for Tribeca Film Festival

Mayim Bialik opened up to fans about a tiff she had with her old friend Neil Patrick Harris that caused trouble in their relationship.

On Tuesday, the “Big Bang Theory” star, 45, and new host of “Jeopardy!” spoke about the incident on “The Late Late Show with James Corden,” Today reports.

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"I have a very bad story about a musical,” she began. “I saw 'Rent.' I was friends with Neil Patrick Harris. This is a terrible story," she said about the 1990s musical.

She later revealed that after the show concluded, she was the only one in the audience that did not rise to their feet to give the future Tony winner, 48, a standing ovation.

"This is a long time ago ... it wasn't my thing," she explained. "But when your friend is in the play and then everybody's clapping at the end and you say to your boyfriend next to you, 'I don’t want to stand for this,' and then you look up and Neil Patrick Harris is looking right at you, it’s a bad day."

Bialik said that despite finding music theater “ridiculous,” she found Harris’ performance “fantastic.”

"I mean, he's amazing but I just wasn’t into the, 'Let’s give a standing ovation.' It wasn’t my thing," she continued. "But that’s the time when you don’t say it out loud because Neil was reading my lips and when I went backstage to say hi to him — we were friends at the time — he said, I kid you not, 'Why did you say you weren’t going to stand up?' He read my lips!"

"We didn’t speak for a long time," she added. "He says that he forgave me and he sent me flowers when he heard that I’m still carrying this terrible (guilt). I mean, I felt terrible. It just wasn’t my thing."

Bialik and Harris became close friends as teenagers while guest-starring on each other’s hit TV shows, the outlet says. In 1990, Bialik appeared in Harris’ medical drama “Doogie Howser, M.D.” The following year, Harris appeared in Bialik’s sitcom “Blossom.”

On Wednesday night, Harris responded to Bialik's comments on "The Late Late Show," tweeting, "Mayim Bialik and I have been friends for over 30 years. Her aversion to musical theater isn’t going to change that."

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Featured Image Photo Credit: Photo by Imeh Akpanudosen/Getty Images / Dia Dipasupil/Getty Images for Tribeca Film Festival