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Has 49ers' Raheem Mostert played his final NFL snap? One doctor thinks so

Raheem Mostert, an overachiever throughout his career, faces an uncertain NFL future after injuring his knee in Sunday's season opener at Detroit. The seven-year veteran was initially thought to be facing an eight-week absence but will now miss the remainder of 2021 after opting—at the urging of his doctors—for season-ending surgery.

Losing Mostert is a serious blow to an inexperienced Niners rushing attack now led by rookies Elijah Mitchell (who should be a popular waiver add in fantasy leagues this week) and Trey Sermon, the latter a healthy scratch in Week 1. Entering the final year of a three-year, $8.7-million contract, it's possible, if not probable, Mostert has played his final down as a 49er. That's assuming Mostert returns to the field at all, which, according to Miami-based physical therapist Dr. Jesse Morse, is no certainty.


Athletes have traditionally had a low success rate returning from microfracture surgery, which orthopedic surgeon Dr. Nirav Pandya suggests could be a possibility for Mostert.

Even the most optimistic among us would agree it's a grim diagnosis for a talented and highly efficient (career 5.7 yards per carry) runner, who, at 29, was already in the autumn of his career, particularly at a physically demanding position that chews players up and spits them out.

Perhaps Mostert will buck the trend and return to full health in his age-30 season next fall, lining up in the Niners backfield or with a different team in 2022. After all, the undrafted Purdue alum has made a career out of defying expectations, bouncing around the league for years as a scarcely-used practice-squadder and special teamer prior to his breakout in 2019 (952 yards from scrimmage with 10 touchdowns). But a player can only take so much punishment and after missing half of last season with a high-ankle sprain and a chunk of 2018 with a fractured forearm, Mostert may ultimately decide his body has had enough.

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